In one of the stories I wrote, yellow fever played a key role; specifically, the yellow fever epidemics of the 1870s, which nearly wiped Memphis, Tennessee off the map. It wasn't until nearly the end of the 19th century that anyone even knew how it was transmitted, or that mosquitos were the vector, so it was truly a hideous plague. I highly recommend
The American Plague by Molly Caldwell Crosby.
Early ads promised all sorts of things as curatives, like this one from 1880:
Warner's Safe* Cure, 1880 
*safe, here, refers to the metal safe in which they kept the cures - you didn't think ad doublespeak was a recent invention, did you? Read more about Warner's
HERE.
A further ad for a quack blood
oxygenator device I've posted about before:
